There are many useful online resources about CUP, however, they can become overwhelming. The resources below are endorsed by our CUP experts as the best sources of support and reliable information.
Understanding Cancer of Unknown Primary PDF Booklet | Cancer Council
Cancer Council provides a downloadable booklet providing information on CUP for patients, carers and others that are affected. This includes explaining CUP, the diagnostic process, treatment, care after treatment and support and services. This booklet is often used as a reference by doctors to explain CUP.
Optimal Care for Cancer of Unknown Primary | Cancer Council
The CUP Optimal Care Pathway provides an overview of what to expect for patient care throughout the journey of a CUP diagnosis, including investigations, treatment and living with cancer.
Our Mob and Cancer provide information and support specifically for Aboriginal and Torres Strait Islander People affected by cancer. This page provides an overview of cancer of unknown primary and its treatment, alongside other resources that might be useful during your care.
The websites listed below are international resources providing detailed information about CUP for patients and carers, including the diagnosis, treatment and management of CUP. While the sections on support services are country-specific, you might find it useful to read other sources of relevant information.
Jo's Friends | UK
Jo’s Friends provides detailed information about CUP for a broad audience including patients, carers, researchers and clinicians. It was established in the UK to raise awareness about CUP and provide support to CUP patients and carers.
Cancer of Unknown Primary | Cancer Research UK
Cancer Research UK provides detailed information about CUP, including diagnosis, treatment and management. There is a section about coping with a CUP diagnosis.
Cancer of Unknown Primary (CUP) | Macmillan Cancer Support (UK)
Macmillan Cancer Support resource provides information about CUP diagnosis with links to relevant tests and procedures.
Cancer of Unknown Primary | American Cancer Society
American Cancer Society provides an “easy reading” section on CUP and an in-depth version. There are downloadable PDFs.
Cancer of Unknown Primary | World CUP Awareness
World Cup Alliance advocate for the interests of people impacted by Cancer of Unknown Primary. They are dedicated to improving the quality of care and life by providing information and support for patients.
Here are the links to other pages for support and services. You may also use the quick links on the right side of the page to navigate.

Most people are diagnosed with cancer of unknown primary (CUP) after they have symptoms or become unwell. Some people may be diagnosed during tests for another health condition. When cancer is suspected, you might be referred for tests or to a specialist.

The treatment you have depends on a number of things, including where the cancer is and your general health. A team of doctors and other professionals discuss the best treatment and care for you. The main treatment for Cancer of Unknown Primary is cancer drugs, most commonly chemotherapy. You may also have radiotherapy to help to control your symptoms and hormone therapy.
